Mystara
Mystara is a campaign setting for Dungeons & Dragons. It originated around the concept of Blackmoor, a mysterious land filled with relics of the past in the form of highly advanced technology mingled with sword and sorcery; the Blackmoor concept evolved into the Known World, which was expanded upon in variod D&D modules and sources.
Mystara includes the Savage Coast, an area under the Red Curse, which eventually kills its inhabitants by mutating them unless the metal cinnabryl is worn in contact with the body.