Small nucleolar RNA Z43
| Small nucleolar RNA Z43 | |
|---|---|
| Identifiers | |
| Other data | |
| PDB structures | PDBe |
Small nucleolar RNA Z43 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Z43 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs[1]. Plant snoRNA Z43 was identified in a screen of Oryza sativa [2].
References
- ^ Galardi, S (2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Mol Cell Biol. 22: 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMID 12215523.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help) - ^ Chen CL, Liang D, Zhou H, Zhuo M, Chen YQ, Qu LH (2003). "The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa". Nucleic Acids Res. 31 (10): 2601–13. PMID 12736310.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
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