Cadaverine - Revision history

WikiCleanerBot: v2.05b - Bot T20 CW#61 - Fix errors for CW project (Reference before punctuation)

2024-10-09T07:01:44Z

v2.05b - Bot T20 CW#61 - Fix errors for CW project (Reference before punctuation)

← Previous revision		Revision as of 07:01, 9 October 2024
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	==Clinical significance==		==Clinical significance==
	[[Semen\|Seminal plasma]] contains cadaverine as basic amines.<ref>{{cite journal\|author= Jana Vitku\|author2= Lucie Kolatorova\|author3=Richard Hampl\|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640966/\|title=Occurrence and reproductive roles of hormones in seminal plasma.\|journal= Basic Clin Androl v.27; 2017 \|year=2017\|volume=27\|issue=19\|pages=\|doi=\|pmid=29046808\|pmc=5640966\|bibcode=\|doi-access=}}</ref> Elevated levels of cadaverine have been found in the urine of some patients with defects in lysine metabolism. The odor commonly associated with [[bacterial vaginosis]] has been linked to cadaverine and [[putrescine]].<ref>{{cite journal\|author=Yeoman, CJ\|author2=Thomas, SM\|author3=Miller, ME\|author4=Ulanov, AV\|author5=Torralba, M\|author6=Lucas, S\|author7=Gillis, M\|author8=Cregger, M\|author9=Gomez, A\|author10=Ho, M\|author11=Leigh, SR\|author12=Stumpf, R\|author13=Creedon, DJ\|author14=Smith, MA\|author15=Weisbaum, JS\|author16=Nelson, KE\|author17=Wilson, BA\|author18=White, BA\|title=A multi-omic systems-based approach reveals metabolic markers of bacterial vaginosis and insight into the disease.\|journal=PLOS ONE\|year=2013\|volume=8\|issue=2\|pages=e56111\|doi=10.1371/journal.pone.0056111\|pmid=23405259\|pmc=3566083\|bibcode=2013PLoSO...856111Y\|doi-access=free}}</ref>.		[[Semen\|Seminal plasma]] contains cadaverine as basic amines.<ref>{{cite journal\|author= Jana Vitku\|author2= Lucie Kolatorova\|author3=Richard Hampl\|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640966/\|title=Occurrence and reproductive roles of hormones in seminal plasma.\|journal= Basic Clin Androl v.27; 2017 \|year=2017\|volume=27\|issue=19\|pages=\|doi=\|pmid=29046808\|pmc=5640966\|bibcode=\|doi-access=}}</ref> Elevated levels of cadaverine have been found in the urine of some patients with defects in lysine metabolism. The odor commonly associated with [[bacterial vaginosis]] has been linked to cadaverine and [[putrescine]].<ref>{{cite journal\|author=Yeoman, CJ\|author2=Thomas, SM\|author3=Miller, ME\|author4=Ulanov, AV\|author5=Torralba, M\|author6=Lucas, S\|author7=Gillis, M\|author8=Cregger, M\|author9=Gomez, A\|author10=Ho, M\|author11=Leigh, SR\|author12=Stumpf, R\|author13=Creedon, DJ\|author14=Smith, MA\|author15=Weisbaum, JS\|author16=Nelson, KE\|author17=Wilson, BA\|author18=White, BA\|title=A multi-omic systems-based approach reveals metabolic markers of bacterial vaginosis and insight into the disease.\|journal=PLOS ONE\|year=2013\|volume=8\|issue=2\|pages=e56111\|doi=10.1371/journal.pone.0056111\|pmid=23405259\|pmc=3566083\|bibcode=2013PLoSO...856111Y\|doi-access=free}}</ref>

	==Derivatives==		==Derivatives==

JOT news: /* History */

2024-10-01T05:49:47Z

History

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	==History==		==History==
	[[Putrescine]]<ref>Ludwig Brieger, "Weitere Untersuchungen über Ptomaine" [Further investigations into ptomaines] (Berlin, Germany: August Hirschwald, 1885), [https://books.google.com/books?id=gqt9piJJ_TkC&dq=putrescin&pg=PA43 page 43].</ref> and cadaverine<ref>Ludwig Brieger, "Weitere Untersuchungen über Ptomaine" [Further investigations into ptomaines] (Berlin, Germany: August Hirschwald, 1885), [https://books.google.com/books?id=gqt9piJJ_TkC&dq=cadaverin&pg=PA39 page 39]. From page 39: Ich nenne das neue Diamin C<sub>5</sub>H<sub>16</sub>N<sub>2</sub>: "Cadaverin", da ausser der empirischen Zussamsetzung, welche die neue Base als ein Hydrür des Neuridins für den flüchtigen Blick erscheinen lässt, keine Anhaltspunkte für die Berechtigung dieser Auffassung zu erheben waren. (I call the new di-amine, C<sub>5</sub>H<sub>16</sub>N<sub>2</sub>, "cadaverine," since besides its empirical composition, which allows the new base to appear superficially as a hydride of neuridine, no clues for the justification of this view arose.)</ref> were first described in 1885 by the [[Berlin]] physician [[Ludwig Brieger]] (1849–1919).<ref>Brief biography of [http://www.sammlungen.hu-berlin.de/dokumente/14948/ Ludwig Brieger] {{Webarchive\|url=https://web.archive.org/web/20111003041704/http://www.sammlungen.hu-berlin.de/dokumente/14948/ \|date=2011-10-03 }} (in German). Biography of [http://jewishencyclopedia.com/articles/3708-brieger-ludwig Ludwig Brieger] in English.</ref>		[[Putrescine]]<ref>Ludwig Brieger, "Weitere Untersuchungen über Ptomaine" [Further investigations into ptomaines] (Berlin, Germany: August Hirschwald, 1885), [https://books.google.com/books?id=gqt9piJJ_TkC&dq=putrescin&pg=PA43 page 43].</ref> and cadaverine<ref>Ludwig Brieger, "Weitere Untersuchungen über Ptomaine" [Further investigations into ptomaines] (Berlin, Germany: August Hirschwald, 1885), [https://books.google.com/books?id=gqt9piJJ_TkC&dq=cadaverin&pg=PA39 page 39]. From page 39: Ich nenne das neue Diamin C<sub>5</sub>H<sub>16</sub>N<sub>2</sub>: "Cadaverin", da ausser der empirischen Zussamsetzung, welche die neue Base als ein Hydrür des Neuridins für den flüchtigen Blick erscheinen lässt, keine Anhaltspunkte für die Berechtigung dieser Auffassung zu erheben waren. (I call the new di-amine, C<sub>5</sub>H<sub>16</sub>N<sub>2</sub>, "cadaverine," since besides its empirical composition, which allows the new base to appear superficially as a hydride of neuridine, no clues for the justification of this view arose.)</ref> were first described in 1885 by the [[Berlin]] physician [[Ludwig Brieger]] (1849–1919).<ref>Brief biography of [http://www.sammlungen.hu-berlin.de/dokumente/14948/ Ludwig Brieger] {{Webarchive\|url=https://web.archive.org/web/20111003041704/http://www.sammlungen.hu-berlin.de/dokumente/14948/ \|date=2011-10-03 }} (in German). Biography of [http://jewishencyclopedia.com/articles/3708-brieger-ludwig Ludwig Brieger] in English.</ref> It was named from the English adjective ''cadaverous''.

	==Receptors==		==Receptors==

JOT news: /* Clinical significance */

2024-10-01T05:45:10Z

Clinical significance

← Previous revision		Revision as of 05:45, 1 October 2024
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	==Clinical significance==		==Clinical significance==
	Elevated levels of cadaverine have been found in the urine of some patients with defects in lysine metabolism. The odor commonly associated with [[bacterial vaginosis]] has been linked to cadaverine and [[putrescine]].<ref>{{cite journal\|author=Yeoman, CJ\|author2=Thomas, SM\|author3=Miller, ME\|author4=Ulanov, AV\|author5=Torralba, M\|author6=Lucas, S\|author7=Gillis, M\|author8=Cregger, M\|author9=Gomez, A\|author10=Ho, M\|author11=Leigh, SR\|author12=Stumpf, R\|author13=Creedon, DJ\|author14=Smith, MA\|author15=Weisbaum, JS\|author16=Nelson, KE\|author17=Wilson, BA\|author18=White, BA\|title=A multi-omic systems-based approach reveals metabolic markers of bacterial vaginosis and insight into the disease.\|journal=PLOS ONE\|year=2013\|volume=8\|issue=2\|pages=e56111\|doi=10.1371/journal.pone.0056111\|pmid=23405259\|pmc=3566083\|bibcode=2013PLoSO...856111Y\|doi-access=free}}</ref>		[[Semen\|Seminal plasma]] contains cadaverine as basic amines.<ref>{{cite journal\|author= Jana Vitku\|author2= Lucie Kolatorova\|author3=Richard Hampl\|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640966/\|title=Occurrence and reproductive roles of hormones in seminal plasma.\|journal= Basic Clin Androl v.27; 2017 \|year=2017\|volume=27\|issue=19\|pages=\|doi=\|pmid=29046808\|pmc=5640966\|bibcode=\|doi-access=}}</ref> Elevated levels of cadaverine have been found in the urine of some patients with defects in lysine metabolism. The odor commonly associated with [[bacterial vaginosis]] has been linked to cadaverine and [[putrescine]].<ref>{{cite journal\|author=Yeoman, CJ\|author2=Thomas, SM\|author3=Miller, ME\|author4=Ulanov, AV\|author5=Torralba, M\|author6=Lucas, S\|author7=Gillis, M\|author8=Cregger, M\|author9=Gomez, A\|author10=Ho, M\|author11=Leigh, SR\|author12=Stumpf, R\|author13=Creedon, DJ\|author14=Smith, MA\|author15=Weisbaum, JS\|author16=Nelson, KE\|author17=Wilson, BA\|author18=White, BA\|title=A multi-omic systems-based approach reveals metabolic markers of bacterial vaginosis and insight into the disease.\|journal=PLOS ONE\|year=2013\|volume=8\|issue=2\|pages=e56111\|doi=10.1371/journal.pone.0056111\|pmid=23405259\|pmc=3566083\|bibcode=2013PLoSO...856111Y\|doi-access=free}}</ref>.

	==Derivatives==		==Derivatives==

BittersweetParadox: Added context

2024-02-25T08:59:05Z

Added context

← Previous revision		Revision as of 08:59, 25 February 2024
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	'''Cadaverine''' is an [[organic compound]] with the formula (CH<sub>2</sub>)<sub>5</sub>(NH<sub>2</sub>)<sub>2</sub>. Classified as a [[diamine]], it is a colorless liquid with an unpleasant odor.<ref name=Ull>{{Ullmann\|doi=10.1002/14356007.a02_001\|title=Amines, Aliphatic\|year=2000\|last1=Eller\|first1=Karsten\|last2=Henkes\|first2=Erhard\|last3=Rossbacher\|first3=Roland\|last4=Höke\|first4=Hartmut\|isbn=3527306730}}</ref> It is present in small quantities in living organisms but is often associated with the [[putrefaction]] of [[Tissue (biology)#Animal tissue\|animal tissue]].		'''Cadaverine''' is an [[organic compound]] with the formula (CH<sub>2</sub>)<sub>5</sub>(NH<sub>2</sub>)<sub>2</sub>. Classified as a [[diamine]], it is a colorless liquid with an unpleasant odor.<ref name=Ull>{{Ullmann\|doi=10.1002/14356007.a02_001\|title=Amines, Aliphatic\|year=2000\|last1=Eller\|first1=Karsten\|last2=Henkes\|first2=Erhard\|last3=Rossbacher\|first3=Roland\|last4=Höke\|first4=Hartmut\|isbn=3527306730}}</ref> It is present in small quantities in living organisms but is often associated with the [[putrefaction]] of [[Tissue (biology)#Animal tissue\|animal tissue]]. Together with [[putrescine]], it is largely responsible for the foul odor of putrefying flesh, but also contributes to other unpleasant odors.

	==Production==		==Production==

1234qwer1234qwer4: added Category:Substances discovered in the 19th century using HotCat

2023-12-25T01:30:38Z

added Category:Substances discovered in the 19th century using HotCat

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	[[Category:Diamines]]		[[Category:Diamines]]
	[[Category:Foul-smelling chemicals]]		[[Category:Foul-smelling chemicals]]
			[[Category:Substances discovered in the 19th century]]

24.60.30.59 at 05:40, 13 December 2023

2023-12-13T05:40:37Z

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	'''Cadaverine''' is an [[organic compound]] with the formula (CH<sub>2</sub>)<sub>5</sub>(NH<sub>2</sub>)<sub>2</sub>. Classified as [[diamine]], it is a colorless liquid with an unpleasant odor.<ref name=Ull>{{Ullmann\|doi=10.1002/14356007.a02_001\|title=Amines, Aliphatic\|year=2000\|last1=Eller\|first1=Karsten\|last2=Henkes\|first2=Erhard\|last3=Rossbacher\|first3=Roland\|last4=Höke\|first4=Hartmut\|isbn=3527306730}}</ref> It is present in small quantities in living organisms but is often associated with the [[putrefaction]] of [[Tissue (biology)#Animal tissue\|animal tissue]].		'''Cadaverine''' is an [[organic compound]] with the formula (CH<sub>2</sub>)<sub>5</sub>(NH<sub>2</sub>)<sub>2</sub>. Classified as a [[diamine]], it is a colorless liquid with an unpleasant odor.<ref name=Ull>{{Ullmann\|doi=10.1002/14356007.a02_001\|title=Amines, Aliphatic\|year=2000\|last1=Eller\|first1=Karsten\|last2=Henkes\|first2=Erhard\|last3=Rossbacher\|first3=Roland\|last4=Höke\|first4=Hartmut\|isbn=3527306730}}</ref> It is present in small quantities in living organisms but is often associated with the [[putrefaction]] of [[Tissue (biology)#Animal tissue\|animal tissue]].

	==Production==		==Production==

Citation bot: Add: doi-access. | Use this bot. Report bugs. | Suggested by Headbomb | #UCB_toolbar

2023-11-25T20:16:20Z

Add: doi-access. | Use this bot. Report bugs. | Suggested by Headbomb | #UCB_toolbar

← Previous revision		Revision as of 20:16, 25 November 2023
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	==Receptors==		==Receptors==
	In [[zebrafish]], the [[trace amine-associated receptor]] 13c (or TAAR13c) has been identified as a high-affinity receptor for cadaverine.<ref>{{cite journal\|author=Li, Q\|author2=Tachie-Baffour, Y\|author3=Liu, Z\|author4=Baldwin, MW\|author5=Kruse, AC\|author6=Liberles, SD\|title=Non-classical amine recognition evolved in a large clade of olfactory receptors.\|journal=eLife\|year=2015\|volume=4\|pages=e10441\|doi=10.7554/eLife.10441\|pmid=26519734\|pmc=4695389}}</ref> In humans, molecular modelling and docking experiments have shown that cadaverine fits into the binding pocket of the human [[TAAR6]] and [[TAAR8]].<ref>{{cite journal\|author=Izquierdo, C\|author2=Gomez-Tamayo, JC\|author3=Nebel, J-C\|author4=Pardo, L\|author5=Gonzalez, A\|title=Identifying human diamine sensors for death related putrescine and cadaverine molecules.\|journal=PLOS Computational Biology\|year=2018\|volume=14\|issue=1\|pages=e1005945\|doi=10.1371/journal.pcbi.1005945\|pmid=29324768\|pmc=5783396\|bibcode=2018PLSCB..14E5945I}}</ref>		In [[zebrafish]], the [[trace amine-associated receptor]] 13c (or TAAR13c) has been identified as a high-affinity receptor for cadaverine.<ref>{{cite journal\|author=Li, Q\|author2=Tachie-Baffour, Y\|author3=Liu, Z\|author4=Baldwin, MW\|author5=Kruse, AC\|author6=Liberles, SD\|title=Non-classical amine recognition evolved in a large clade of olfactory receptors.\|journal=eLife\|year=2015\|volume=4\|pages=e10441\|doi=10.7554/eLife.10441\|pmid=26519734\|pmc=4695389 \|doi-access=free }}</ref> In humans, molecular modelling and docking experiments have shown that cadaverine fits into the binding pocket of the human [[TAAR6]] and [[TAAR8]].<ref>{{cite journal\|author=Izquierdo, C\|author2=Gomez-Tamayo, JC\|author3=Nebel, J-C\|author4=Pardo, L\|author5=Gonzalez, A\|title=Identifying human diamine sensors for death related putrescine and cadaverine molecules.\|journal=PLOS Computational Biology\|year=2018\|volume=14\|issue=1\|pages=e1005945\|doi=10.1371/journal.pcbi.1005945\|pmid=29324768\|pmc=5783396\|bibcode=2018PLSCB..14E5945I \|doi-access=free }}</ref>

	==Clinical significance==		==Clinical significance==

GhostInTheMachine: Shorten short description — WP:SDSHORT

2023-07-05T10:09:50Z

Shorten short description — WP:SDSHORT

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	{{~~short~~ description\|Foul-smelling diamine compound ~~produced by the putrefaction of animal tissue~~}}		{{Short description\|Foul-smelling diamine compound}}
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GhostInTheMachine: Reverting edit(s) by 66.56.217.15 (talk) to rev. 1146700033 by M97uzivatel: non-constructive (RW 16.1)

2023-07-05T10:09:16Z

Reverting edit(s) by 66.56.217.15 (talk) to rev. 1146700033 by M97uzivatel: non-constructive (RW 16.1)

← Previous revision		Revision as of 10:09, 5 July 2023
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	{{short description\|Foul-smelling diamine compound produced by the putrefaction of animal tissue~~. When someone dies this is one of the 2 foul smells that the body will give off, the other one is [[putricene]].~~}}		{{short description\|Foul-smelling diamine compound produced by the putrefaction of animal tissue}}
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66.56.217.15 at 21:59, 4 July 2023

2023-07-04T21:59:25Z

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	{{short description\|Foul-smelling diamine compound produced by the putrefaction of animal tissue}}		{{short description\|Foul-smelling diamine compound produced by the putrefaction of animal tissue. When someone dies this is one of the 2 foul smells that the body will give off, the other one is [[putricene]].}}
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